Biasin, MaraMaraBiasinBIANCO, ANDREAANDREABIANCOPARESCHI, GiovanniGiovanniPARESCHICavalleri, AdalbertoAdalbertoCavalleriCavatorta, ClaudiaClaudiaCavatortaFenizia, ClaudioClaudioFeniziaGALLI, PaolaPaolaGALLILESSIO, LuigiLuigiLESSIOLualdi, ManuelaManuelaLualdiTombetti, EnricoEnricoTombettiAmbrosi, AlessandroAlessandroAmbrosiREDAELLI, Edoardo Maria AlbertoEdoardo Maria AlbertoREDAELLISaulle, IrmaIrmaSaulleTrabattoni, DariaDariaTrabattoniZANUTTA, AlessioAlessioZANUTTAClerici, MarioMarioClerici2023-04-182023-04-1820212045-2322http://hdl.handle.net/20.500.12386/34084The potential virucidal effects of UV-C irradiation on SARS-CoV-2 were experimentally evaluated for different illumination doses and virus concentrations (1000, 5, 0.05 MOI). At a virus density comparable to that observed in SARS-CoV-2 infection, an UV-C dose of just 3.7 mJ/cm2 was sufficient to achieve a more than 3-log inactivation without any sign of viral replication. Moreover, a complete inactivation at all viral concentrations was observed with 16.9 mJ/cm2. These results could explain the epidemiological trends of COVID-19 and are important for the development of novel sterilizing methods to contain SARS-CoV-2 infection.ELETTRONICOenUV-C irradiation is highly effective in inactivating SARS-CoV-2 replicationArticle10.1038/s41598-021-85425-w2-s2.0-85102734901https://www.nature.com/articles/s41598-021-85425-whttps://api.elsevier.com/content/abstract/scopus_id/85102734901FIS/05 - ASTRONOMIA E ASTROFISICA