Fatemi, S.S.FatemiAbbene, L.L.AbbenePrincipato, F.F.PrincipatoButtacavoli, A.A.ButtacavoliAURICCHIO, NATALIANATALIAAURICCHIOCAROLI, EZIOEZIOCAROLIBASILI, ANGELOANGELOBASILIZambelli, N.N.ZambelliBenassi, G.G.BenassiBettelli, M.M.BettelliZanettini, S.S.ZanettiniZappettini, A.A.ZappettiniBortolussi, S.S.BortolussiMagni, C.C.MagniPostuma, I.I.PostumaAltieri, S.S.AltieriProtti, N.N.Protti2021-02-152021-02-152018978-1-5386-8494-8978-1-5386-8495-51082-3654http://hdl.handle.net/20.500.12386/30374The National Institute of Nuclear Physics (INFN) is supporting the 3CaTS project with the aim of developing a new Single Photon Emission Computed Tomography (SPECT) system for real time 10 B therapeutic dose monitoring in the binary experimental hadron therapy called Boron Neutron Capture Therapy (BNCT). BNCT is a highly selective tumour treatment based on the neutron capture reaction 10 B(n,α) 7 Li. The secondary particles have a high LET with ranges in tissues of the order of 10 μm (thus less than the mean cell diameter of few tens μm). Targeting the 10 B delivery towards cancer, the released energy lethally damages only the malignant cells sparing the normal tissues, thus enabling a cell-level selective treatment. To properly exploit this selectivity it is mandatory to know the 10 B spatial distribution inside patients body during neutron irradiation. This can be achieved by detecting the 478 keV γ ray emitted in the 94% of 10 B capture reactions by a SPECT system. A 3D CZT drift strip detector with a sensitive volume of 20x20x5 mm 3 was developed, able to perform high-resolution X-ray and γ ray spectroscopic imaging (10-1000 keV). The detector signals are analysed by a custom digital multi-channel electronics, based on two pipelined fast and slow analysis, able to perform multi-parameter analysis and fine temporal coincidences (<; 20 ns). Energy resolution of 3.3% (4 keV) and 2% (13 keV) FWHM was measured, with uncollimated sources and no corrections, at 122 keV and 662 keV, respectively.ELETTRONICOenConference paper10.1109/NSSMIC.2018.88243812-s2.0-85073122028https://ieeexplore.ieee.org/document/8824381FIS/01 - FISICA SPERIMENTALEERC sectors::Physical Sciences and Engineering::PE3 Condensed matter physics: structure, electronic properties, fluids, nanosciences