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UV-C irradiation is highly effective in inactivating SARS-CoV-2 replication

Journal
Date Issued
2021
Author(s)
Biasin, Mara
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Cavalleri, Adalberto
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Cavatorta, Claudia
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Fenizia, Claudio
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Lualdi, Manuela
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Tombetti, Enrico
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Ambrosi, Alessandro
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Saulle, Irma
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Trabattoni, Daria
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Clerici, Mario
DOI
Abstract
The potential virucidal effects of UV-C irradiation on SARS-CoV-2 were experimentally evaluated for different illumination doses and virus concentrations (1000, 5, 0.05 MOI). At a virus density comparable to that observed in SARS-CoV-2 infection, an UV-C dose of just 3.7 mJ/cm2 was sufficient to achieve a more than 3-log inactivation without any sign of viral replication. Moreover, a complete inactivation at all viral concentrations was observed with 16.9 mJ/cm2. These results could explain the epidemiological trends of COVID-19 and are important for the development of novel sterilizing methods to contain SARS-CoV-2 infection.
Volume
11
Issue
1
Uri
Url
Issn Identifier
2045-2322
Rights
open.access
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