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|Title:||High performance 3D CZT spectro-imager for BNCT-SPECT: preliminary characterization||Authors:||Fatemi, S.
|Issue Date:||2018||Volume:||2018 IEEE Nuclear Science Symposium and Medical Imaging Conference Proceedings (NSS/MIC)||Series:||IEEE CONFERENCE RECORD - NUCLEAR SCIENCE SYMPOSIUM & MEDICAL IMAGING CONFERENCE||First Page:||1||Abstract:||The National Institute of Nuclear Physics (INFN) is supporting the 3CaTS project with the aim of developing a new Single Photon Emission Computed Tomography (SPECT) system for real time 10 B therapeutic dose monitoring in the binary experimental hadron therapy called Boron Neutron Capture Therapy (BNCT). BNCT is a highly selective tumour treatment based on the neutron capture reaction 10 B(n,α) 7 Li. The secondary particles have a high LET with ranges in tissues of the order of 10 μm (thus less than the mean cell diameter of few tens μm). Targeting the 10 B delivery towards cancer, the released energy lethally damages only the malignant cells sparing the normal tissues, thus enabling a cell-level selective treatment. To properly exploit this selectivity it is mandatory to know the 10 B spatial distribution inside patients body during neutron irradiation. This can be achieved by detecting the 478 keV γ ray emitted in the 94% of 10 B capture reactions by a SPECT system. A 3D CZT drift strip detector with a sensitive volume of 20x20x5 mm 3 was developed, able to perform high-resolution X-ray and γ ray spectroscopic imaging (10-1000 keV). The detector signals are analysed by a custom digital multi-channel electronics, based on two pipelined fast and slow analysis, able to perform multi-parameter analysis and fine temporal coincidences (<; 20 ns). Energy resolution of 3.3% (4 keV) and 2% (13 keV) FWHM was measured, with uncollimated sources and no corrections, at 122 keV and 662 keV, respectively.||Conference Name:||2018 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)||Conference Place:||Sydney, Australia,||Conference Date:||10-17 November, 2018||URI:||http://hdl.handle.net/20.500.12386/30374||URL:||https://ieeexplore.ieee.org/document/8824381||ISSN:||1082-3654||ISBN:||978-1-5386-8494-8
|Appears in Collections:||3.01 Contributi in Atti di convegno|
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checked on Jun 19, 2021
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