Please use this identifier to cite or link to this item:
http://hdl.handle.net/20.500.12386/30374
Title: | High performance 3D CZT spectro-imager for BNCT-SPECT: preliminary characterization | Authors: | Fatemi, S. Abbene, L. Principato, F. Buttacavoli, A. AURICCHIO, NATALIA CAROLI, EZIO BASILI, ANGELO Zambelli, N. Benassi, G. Bettelli, M. Zanettini, S. Zappettini, A. Bortolussi, S. Magni, C. Postuma, I. Altieri, S. Protti, N. |
Issue Date: | 2018 | Volume: | 2018 IEEE Nuclear Science Symposium and Medical Imaging Conference Proceedings (NSS/MIC) | Series: | IEEE CONFERENCE RECORD - NUCLEAR SCIENCE SYMPOSIUM & MEDICAL IMAGING CONFERENCE | First Page: | 1 | Abstract: | The National Institute of Nuclear Physics (INFN) is supporting the 3CaTS project with the aim of developing a new Single Photon Emission Computed Tomography (SPECT) system for real time 10 B therapeutic dose monitoring in the binary experimental hadron therapy called Boron Neutron Capture Therapy (BNCT). BNCT is a highly selective tumour treatment based on the neutron capture reaction 10 B(n,α) 7 Li. The secondary particles have a high LET with ranges in tissues of the order of 10 μm (thus less than the mean cell diameter of few tens μm). Targeting the 10 B delivery towards cancer, the released energy lethally damages only the malignant cells sparing the normal tissues, thus enabling a cell-level selective treatment. To properly exploit this selectivity it is mandatory to know the 10 B spatial distribution inside patients body during neutron irradiation. This can be achieved by detecting the 478 keV γ ray emitted in the 94% of 10 B capture reactions by a SPECT system. A 3D CZT drift strip detector with a sensitive volume of 20x20x5 mm 3 was developed, able to perform high-resolution X-ray and γ ray spectroscopic imaging (10-1000 keV). The detector signals are analysed by a custom digital multi-channel electronics, based on two pipelined fast and slow analysis, able to perform multi-parameter analysis and fine temporal coincidences (<; 20 ns). Energy resolution of 3.3% (4 keV) and 2% (13 keV) FWHM was measured, with uncollimated sources and no corrections, at 122 keV and 662 keV, respectively. | Conference Name: | 2018 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) | Conference Place: | Sydney, Australia, | Conference Date: | 10-17 November, 2018 | URI: | http://hdl.handle.net/20.500.12386/30374 | URL: | https://ieeexplore.ieee.org/document/8824381 | ISSN: | 1082-3654 | ISBN: | 978-1-5386-8494-8 978-1-5386-8495-5 |
DOI: | 10.1109/NSSMIC.2018.8824381 | Fulltext: | open |
Appears in Collections: | 3.01 Contributi in Atti di convegno |
Files in This Item:
File | Description | Size | Format | |
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Fatemi-High performance 3D CZT-IEEE Conf Rec 2018free.pdf | postprint | 817.53 kB | Adobe PDF | View/Open |
08824381.pdf | [Administrators only] | 1.32 MB | Adobe PDF |
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